Research Home

Suril Gohel, PhD

The neuroinformatics lab at Rutgers focuses on understanding human brain function during resting state and in task conditions, and how that is disrupted by cognitive challenges and in neuro-clinical populations. Specifically, we use multiband, neuroimaging data to understand and quantify frequency-specific changes in functional brain integration. Using multiband fMRI acquisition sequences, we have shown the presence of functional integration between brain regions in BOLD signal frequencies higher than 0.1 Hz (Gohel et al. 2015). These results have further led to quantification of frequency-specific differences in BOLD signal power in drug-naive schizophrenia patients compared to healthy volunteers (Gohel et al., 2018). Secondarily, our research focuses on using advanced neuroimaging data collection and analytical strategies to understand functional brain disruptions in clinical populations.  We have successfully used functional neuroimaging to quantify brain disruptions in a variety of neurological disorders, including brain injury, (Gohel, Bharath et al., 2015), and brain tumors (Gohel et al. 2019) as well as mental health disorders including addiction (Filbey, Gohel, et al., 2018) and psychosis (Gohel et al., 2018).  Finally, we also focus on methods of development for quantifying neuronal and neurophysiological components of BOLD fMRI signal and its disruptions in clinical population

Mohamed Ahmed

PhD student

ma1168@shp.rutgers.edu

Aaron Ostrovsky

PhD student

aso37@shp.rutgers.edu

Sandhya Bohini

PhD student

bohinisa@shp.rutgers.edu

Prashant Ingle

PhD student

pi45@shp.rutgers.edu

Chinedum Ehiobuche

Master’student

cje56@shp.rutgers.edu

Rabab Alnakhli

Master’student

raa173@shp.rutgers.edu

Are you interested in collaboration/engaging with research?

Please email at  suril.gohel@rutgers.edu

  1. Gohel S, Laino ME, Rajeev-Kumar G, Jenabi M, Peck K, Hatzoglou V, Tabar V, Holodny AI, Vachha B. Resting-State Functional Connectivity of the Middle Frontal Gyrus Can Predict Language Lateralization in Patients with Brain Tumors. AJNR Am J Neuroradiol. 2019 Feb;40(2):319-325. doi: 10.3174/ajnr.A5932. Epub 2019 Jan 10. PubMed PMID: 30630835; PubMed Central PMCID: PMC6375738.
  2. Kaku SM, Jayashankar A, Girimaji SC, Bansal S, Gohel S, Bharath RD, Srinath S. Early childhood network alterations in severe autism. Asian J Psychiatr. 2019 Jan;39:114-119. doi: 10.1016/j.ajp.2018.12.009. Epub 2018 Dec 21. PubMed PMID: 30610990.
  3. Gohel S, Gallego JA, Robinson DG, DeRosse P, Biswal B, Szeszko PR. Frequency specific resting state functional abnormalities in psychosis. Hum Brain Mapp. 2018 Nov;39(11):4509-4518. doi: 10.1002/hbm.24302. Epub 2018 Aug 30. PubMed PMID: 30160325.
  4. Filbey FM, Gohel S, Prashad S, Biswal BB. Differential associations of combined vs. isolated cannabis and nicotine on brain resting state networks. Brain Struct Funct. 2018 Sep;223(7):3317-3326. doi: 10.1007/s00429-018-1690-5. Epub 2018 Jun 7. PubMed PMID: 29882015; PubMed Central PMCID: PMC6286234.
  5. Egbert AR, Biswal B, Karunakaran K, Gohel S, Pluta A, Wolak T, Szymańska B, Firląg-Burkacka E, Sobańska M, Gawron N, Bieńkowski P, Sienkiewicz-Jarosz H, Ścińska-Bieńkowska A, Bornstein R, Rao S, Łojek E. Age and HIV effects on resting state of the brain in relationship to neurocognitive functioning. Behav Brain Res. 2018 May 15;344:20-27. doi: 10.1016/j.bbr.2018.02.007. Epub 2018 Feb 6. PubMed PMID: 29425918.
  6. Toich JTF, Taylor PA, Holmes MJ, Gohel S, Cotton MF, Dobbels E, Laughton B, Little F, van der Kouwe AJW, Biswal B, Meintjes EM. Functional Connectivity Alterations between Networks and Associations with Infant Immune Health within Networks in HIV Infected Children on Early Treatment: A Study at 7 Years. Front Hum Neurosci. 2017;11:635. doi: 10.3389/fnhum.2017.00635. eCollection 2017. PubMed PMID: 29375341; PubMed Central PMCID: PMC5768628.
  7. Di X, Gohel S, Thielcke A, Wehrl HF, Biswal BB. Do all roads lead to Rome? A comparison of brain networks derived from inter-subject volumetric and metabolic covariance and moment-to-moment hemodynamic correlations in old individuals. Brain Struct Funct. 2017 Nov;222(8):3833-3845. doi: 10.1007/s00429-017-1438-7. Epub 2017 May 4. PubMed PMID: 28474183.
  8. Fan J, Taylor PA, Jacobson SW, Molteno CD, Gohel S, Biswal BB, Jacobson JL, Meintjes EM. Localized reductions in resting-state functional connectivity in children with prenatal alcohol exposure. Hum Brain Mapp. 2017 Oct;38(10):5217-5233. doi: 10.1002/hbm.23726. Epub 2017 Jul 22. PubMed PMID: 28734059; PubMed Central PMCID: PMC6377933.
  9. Bharath RD, Panda R, Reddam VR, Bhaskar MV, Gohel S, Bhardwaj S, Prajapati A, Pal PK. A Single Session of rTMS Enhances Small-Worldness in Writer’s Cramp: Evidence from Simultaneous EEG-fMRI Multi-Modal Brain Graph. Front Hum Neurosci. 2017;11:443. doi: 10.3389/fnhum.2017.00443. eCollection 2017. PubMed PMID: 28928648; PubMed Central PMCID: PMC5591831.
  10. Ray S, Biswal BB, Aya A, Gohel S, Srinagesh A, Hanson C, Hanson SJ. Modeling Causal Relationships among Brain Areas in the Mesocorticolimbic System during Resting-State in Cocaine Users Utilizing a Graph Theoretic Approach. J Alcohol Drug Depend. 2017 Aug;5(4). doi: 10.4172/2329-6488.1000279. Epub 2017 Aug 31. PubMed PMID: 29034263; PubMed Central PMCID: PMC5635998.
  11. Bharath RD, Chaitanya G, Panda R, Raghavendra K, Sinha S, Sahoo A, Gohel S, Biswal BB, Satishchandra P. Reduced small world brain connectivity in probands with a family history of epilepsy. Eur J Neurol. 2016 Dec;23(12):1729-1737. doi: 10.1111/ene.13104. Epub 2016 Aug 26. PubMed PMID: 27564534.
  12. Yuan R, Di X, Taylor PA, Gohel S, Tsai YH, Biswal BB. Functional topography of the thalamocortical system in human. Brain Struct Funct. 2016 May;221(4):1971-84. doi: 10.1007/s00429-015-1018-7. Epub 2015 Apr 30. PubMed PMID: 25924563; PubMed Central PMCID: PMC6363530.
  13. Ray S, Gohel S, Biswal BB. Altered Functional Connectivity Strength in Abstinent Chronic Cocaine Smokers Compared to Healthy Controls. Brain Connect. 2015 Oct;5(8):476-86. doi: 10.1089/brain.2014.0240. Epub 2015 Aug 6. PubMed PMID: 26005203; PubMed Central PMCID: PMC4601553.
  14. Bharath RD, Munivenkatappa A, Gohel S, Panda R, Saini J, Rajeswaran J, Shukla D, Bhagavatula ID, Biswal BB. Recovery of resting brain connectivity ensuing mild traumatic brain injury. Front Hum Neurosci. 2015;9:513. doi: 10.3389/fnhum.2015.00513. eCollection 2015. PubMed PMID: 26441610; PubMed Central PMCID: PMC4585122.
  15. Bharath RD, Biswal BB, Bhaskar MV, Gohel S, Jhunjhunwala K, Panda R, George L, Gupta AK, Pal PK. Repetitive transcranial magnetic stimulation induced modulations of resting state motor connectivity in writer’s cramp. Eur J Neurol. 2015 May;22(5):796-805, e53-4. doi: 10.1111/ene.12653. Epub 2015 Jan 26. PubMed PMID: 25623591.
  16. Gohel SR, Biswal BB. Functional integration between brain regions at rest occurs in multiple-frequency bands. Brain Connect. 2015 Feb;5(1):23-34. doi: 10.1089/brain.2013.0210. Epub 2014 Jun 25. PubMed PMID: 24702246; PubMed Central PMCID: PMC4313418.
  17. Jaswal R, Gohel S, Biswal BB, Alvarez TL. Task-modulated coactivation of vergence neural substrates. Brain Connect. 2014 Oct;4(8):595-607. doi: 10.1089/brain.2013.0216. Epub 2014 Jun 19. PubMed PMID: 24773099; PubMed Central PMCID: PMC4202927.
  18. Alvarez TL, Jaswal R, Gohel S, Biswal BB. Functional activity within the frontal eye fields, posterior parietal cortex, and cerebellar vermis significantly correlates to symmetrical vergence peak velocity: an ROI-based, fMRI study of vergence training. Front Integr Neurosci. 2014;8:50. doi: 10.3389/fnint.2014.00050. eCollection 2014. PubMed PMID: 24987340; PubMed Central PMCID: PMC4060559.
  19. Di X, Gohel S, Kim EH, Biswal BB. Task vs. rest-different network configurations between the coactivation and the resting-state brain networks. Front Hum Neurosci. 2013;7:493. doi: 10.3389/fnhum.2013.00493. eCollection 2013. PubMed PMID: 24062654; PubMed Central PMCID: PMC3775427.
  20. Taylor PA, Gohel S, Di X, Walter M, Biswal BB. Functional covariance networks: obtaining resting-state networks from intersubject variability. Brain Connect. 2012;2(4):203-17. doi: 10.1089/brain.2012.0095. Epub 2012 Aug 28. PubMed PMID: 22765879; PubMed Central PMCID: PMC3621593.
  21. Wang JH, Zuo XN, Gohel S, Milham MP, Biswal BB, He Y. Graph theoretical analysis of functional brain networks: test-retest evaluation on short- and long-term resting-state functional MRI data. PLoS One. 2011;6(7):e21976. doi: 10.1371/journal.pone.0021976. Epub 2011 Jul 19. PubMed PMID: 21818285; PubMed Central PMCID: PMC3139595.
  22. Alkan Y, Alvarez TL, Gohel S, Taylor PA, Biswal BB. Functional connectivity in vergence and saccade eye movement tasks assessed using Granger Causality analysis. Conf Proc IEEE Eng Med Biol Soc. 2011;2011:8114-7. doi: 10.1109/IEMBS.2011.6092001. PubMed PMID: 22256225.
  23. Alvarez TL, Vicci VR, Alkan Y, Kim EH, Gohel S, Barrett AM, Chiaravalloti N, Biswal BB. Vision therapy in adults with convergence insufficiency: clinical and functional magnetic resonance imaging measures. Optom Vis Sci. 2010 Dec;87(12):E985-1002. doi: 10.1097/OPX.0b013e3181fef1aa. PubMed PMID: 21057347; PubMed Central PMCID: PMC3134155.
  24. Alvarez TL, Alkan Y, Gohel S, Douglas Ward B, Biswal BB. Functional anatomy of predictive vergence and saccade eye movements in humans: a functional MRI investigation. Vision Res. 2010 Oct 12;50(21):2163-75. doi: 10.1016/j.visres.2010.08.018. Epub 2010 Aug 20. PubMed PMID: 20728462.
  25. Biswal BB, Mennes M, Zuo XN, Gohel S, Kelly C, Smith SM, Beckmann CF, Adelstein JS, Buckner RL, Colcombe S, Dogonowski AM, Ernst M, Fair D, Hampson M, Hoptman MJ, Hyde JS, Kiviniemi VJ, Kötter R, Li SJ, Lin CP, Lowe MJ, Mackay C, Madden DJ, Madsen KH, Margulies DS, Mayberg HS, McMahon K, Monk CS, Mostofsky SH, Nagel BJ, Pekar JJ, Peltier SJ, Petersen SE, Riedl V, Rombouts SA, Rypma B, Schlaggar BL, Schmidt S, Seidler RD, Siegle GJ, Sorg C, Teng GJ, Veijola J, Villringer A, Walter M, Wang L, Weng XC, Whitfield-Gabrieli S, Williamson P, Windischberger C, Zang YF, Zhang HY, Castellanos FX, Milham MP. Toward discovery science of human brain function. Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4734-9. doi: 10.1073/pnas.0911855107. Epub 2010 Feb 22. PubMed PMID: 20176931; PubMed Central PMCID: PMC2842060.
Dept. Home