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Soha Saleh, Ph.D.
Faculty Profile

Soha Saleh, Ph.D.

The Neurophysiology and Rehabilitation Innovations Lab

The NeuREI lab applies knowledge of neurophysiology to advance rehabilitation research.  Its mission is to improve function and quality of life for individuals with motor and cognitive disabilities.

 

The NeuREI lab areas of research include:

  • Developing neuroimaging based prognosis models of recovery post stroke
  • Investigating cognitive-motor interactions and neuromodulation methods to promote neuroplasticity
  • Using multidisciplinary approach involving structural and functional imaging and electrophysiological techniques and behavioral assessment, combined with advanced signal processing and analysis.

Keywords: Neuroimaging, Signal Processing, Image Processing, Brain Connectivity, Electrophysiology, Neurorehabilitation

Michael Glassen
Research Engineer
Email: mglassen@shp.rutgers.edu

Grant Funding

Title: Functional and neurophysiological effects of a progressive robot assisted gait intervention early post stroke

Role: Principal Investigator

Sponsor Agency: National Institute of Health, National Institute of Child Health and Human Development

Brief Overview of Aims: This research project is the first comprehensive study to evaluate a progressive and adaptive assist-as-needed intensive exoskeleton robotic (ER) intervention (30 hours of training) in the acute phase post stroke and its effect on functional recovery, neuromuscular adaptations, and neuroplasticity. Longitudinal measures of functional recovery and modulation of neuromuscular activations during walking, structural and resting-state functional MRI connectivity, and cortico-muscular connectivity (CMC) (using TMS, EEG, and EMG) will be acquired and used to model prognoses of recovery and understand the effect of ER assisted training.

Total Dollar Amount: $3,547,908

Funding Period: August 15, 2019  – November 30, 2024


Title: Cortical control of walking; brain plasticity following exoskeleton training in Incomplete Spinal Cord Injury

Role: Principal Investigator

Sponsor Agency: New Jersey Commission on Spinal Cord Injury Research

Brief Overview of Aims: This study investigates the cortical modulation of muscle activation and within-brain activation during walking, and the re-organization of cortical control of walking after SCI and intensive exoskeleton-assisted training.

Total Dollar Amount: $200,000

Funding Period: June 1, 2018 – May 31, 2024 (no cost extension)


Title: Combining Physical and Mental Practice for the Rehabilitation of Upper Extremity Movement Impairments Secondary to Traumatic Brain Injury

Role: Principal Investigator

Sponsor Agency: New Jersey Commission on Brain Injury Research

Brief Overview of Aims: This study investigates the effect of motor imagery and performance based feedback on improving rehabilitation outcomes.

Total Dollar Amount: $179,240

Funding Period: July 1, 2017 – May 31, 2021 (completed)

Year Name of Honor
2015 Outstanding Research Scholar: Lebanese International University
2015 Best Conference Paper Award: 2015 Global Health Annual Meeting
2014 Best Paper Award: Neurorehabilitation and Neural Repair
2010 Best Paper Award: VIII International Conference on Disability, Virtual Reality and Associated Technologies
2009 Outstanding Performance Award: Dana Knox Showcase Committee, NJIT
2006 Best Student Capstone Design Project: Annual Engineering Exhibition

Selected Publications

  1. Brihmat N, Allexandre D, Bayram MB, Saleh S, Guan X, Yue Guang H, Zhong J, Forrest GF. Safety and effects of a therapeutic 15 Hz rTMS protocol administered at different suprathreshold intensities in able-bodied individuals. J Neurophysiol. 2023 Jan 1;129(1):56-65. doi: 10.1152/jn.00268.2022. Epub 2022 Dec 7. PMID: 36475885.
  2. Saleh S, Glassen M, Momeni K, Ravi M, Bheemreddy A, Hoxha S, Garbarini E, Yue GH, Forrest, GF. Corticomuscular Connectivity during Walking in Able Bodied and Individuals with Incomplete Spinal Cord Injury. Annu Int Conf IEEE Eng Med Biol Soc. 2022 Jul;2022:2332-2335. doi:
    10.1109/EMBC48229.2022.9871197. PMID: 36086198.
  3. Patel J, Pattison I, Glassen M, Saleh S, Qui Q, Fluet G, Kaplan E, Tunik E, Nolan KJ., Merians A,  Adamovich S. EEG Based Resting State Connectivity Changes in the Motor Cortex Associated with Upper Limb Motor Recovery in the Subacute Period Post-Stroke. Annu Int Conf IEEE Eng Med Biol Soc, 2022.
  4. Alivar A, Glassen M, Hoxha A, Allexandre D, Yue G, Saleh S, Relationship between DTI Brain Connectivity and Functional Performance in Individuals with Traumatic Brain Injury, Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:3256-3259. doi: 10.1109/EMBC44109.2020.9176130. PMID: 33018699.
  5. Saleh S, Sandroff BM, Vitiello T, Owoeye O, Hoxha A, Hake P, Goverover Y, Wylie G, Yue GH, DeLuca J. The Role of Premotor Areas in Dual Tasking in Healthy Controls and Persons With Multiple Sclerosis: An fNIRS Imaging Study. Front Behav Neurosci. 2018;12:296. PubMed PMID: 30618658; PubMed Central PMCID: PMC6297844.

Full Publication List

For more information on the research at the NeuREI lab, please contact Professor Saleh at salehsh@shp.rutgers.edu.

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