Study Eligibility

To be eligible for to participate in this study, you must be:

• Age 18-55 years old
• On Buprenorphine treatment
• Have a positive urine toxicology screen for non-prescription opioids
• Be in good health as verified by screening examination
• Able to read English and provide informed consent
• Woman who agrees to use reliable forms of birth control such as condoms, birth control, vaginal rings, skin patch
• On blood pressure medication if you have high blood pressure

You are not eligible to participate in this study if you:

• Meet the criteria for moderate to severe substance use disorder
• You are experiencing severe mental health issues, like being psychotic or having serious psychiatric problems (for example, feeling suicidal or currently having mania)
• Have uncontrolled high blood pressure
• Are a woman who is pregnant or nursing or refuse to use a reliable form of birth control
• Your initial EKG shows any serious heart rhythm problems

All information will be kept confidential.