Frederick Coffman, Ph.D.
Associate Professor
Department: Health Informatics
Program: Health Informatics
Phone: (973) 972-8190
Email: frederick.coffman@rutgers.edu
Joint Appointment: Associate Professor
Department : Pathology & Laboratory Medicine
School: New Jersey Medical School, Newark NJ
Office location:
65 Bergen Street, Room 350
Newark, NJ 07101
About
Dr. Frederick Coffman is an Associate Professor in the School of Health Professions with joint appointments in the Department of Health Informatics and the Department of Physiciasn Assistant Studies and Practice, as well as an adjunct appointment in the Department of Pathology in the Rutgers New Jersey Medical School. He earned a BS in Chemistry from California State University at Long Beach and a Ph.D. in Biochemistry from the University of California at Riverside.
Prior to joining the School of Health Professions, Dr. Coffman spent over 25 years as a medical school faculty member (Hahnemann University and New Jersey Medical School). He has performed basic and applied research in the areas of cancer and immunology; his areas of focus include the synergistic enhancement of TNF-mediated tumor cell killing by specific classes of DNA topoisomerase II inhibitors, the function of the chitinase family protein YKL-40 as a tumor cell survival factor, the regulation of DNA replication initiation in leukemia cells, and most recently differences in the biophysical properties of low grade and highly malignant cancer cells. He has served on the doctoral thesis advisory committees of over 100 graduate students, and has served as Associate Director of three doctoral graduate programs and multiple graduate school courses. He has given lectures in over 27 different graduate school, medical school, dental school, and health professions courses. He has published his research in numerous peer-reviewed publications, written invited reviews and book chapters, and served as a panelist on national, state and foundation study sections.
He has presented his work at national meetings. He is currently involved in several research projects focused on cancer informatics and the biophysical profiling of cancer cells. In the Biomedical Informatics graduate program, Dr. Coffman mentors graduate students and serves as course director for the Biomedical Imaging, Disease Processes and Systems, and Translational Informatics: Biomarkers and Personalized Healthcare courses. In the Physician Assistant program, Dr. Coffman has served as course director for the Biochemistry, Genetics and Pathology courses, and currently serves as co-course director for Scientific Foundations of Medicine and Pathophysiology.
Education
B.S., California State University
Ph.D., University of California
Professional Achievements
Research
Publications
| Title | Authors | Where and When | ||
Physician review of a celiac disease risk estimation and decision-making expert system. |
Pastore RL, Murray JA, Coffman FD, Mitrofanova A, Srinivasan S. |
Journal of the American College of Nutrition. 1-7, 2019. |
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Investigation of a novel decision support metric for head and neck adaptive radiation therapy using a real-time in vivo portal dosimetry system. |
Lim SB; Tsai CJ; Yu Y; Greer P; Fuangrod T; Hwang K; Fontenla S; Coffman F; Lee N; Lovelock DM. |
Technology in Cancer Research & Treatment, 18: 1-6 (2019). |
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Three-dimensional cellular Raman analysis: evidence of highly ordered lipids within cell nuclei. |
Ramamurthy B, Cohen S, Canales M, and Coffman FD. |
Journal of Histochemistry & Cytochemistry. 66(12):889-902, 2018 Dec. |
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Effects of vitamin D derivatives on differentiation, cell cycle and apoptosis in hematological malignancies |
Studzinski GP, Gocek E, Coffman F, Danilenko M |
Chapter 94, Vitamin D, 4th Edition, Volume 2: Health, Disease and Therapeutics; David Feldman Ed., Academic Press. eBook ISBN: 9780128099643; Hardcover ISBN: 9780128099636 (2017) |
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Structural basis of CXCR4 recognition by a constitutively monomeric CXCL12 and implications for receptor activation. |
Ziarek J, Kleist A, London N, Raveh B, Malik R, Montpas N, Bonneterre J, St-Onge G, Kremer KN, DiCosmo-Ponticello C, Koplonski CA, Roy I, Stephens BS, Thelen S, Veldkamp CT, Coffman FD, Cohen MC, Dwinell MB, Thelen M, Hedin KE, Peterson FC, Marchese A, Heveker N, Volkman BF |
Sci Signal 10: eaah5756. 2017 |
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Portrait of a dying cell. |
Lau K. Coffman F, Ramamurthy B |
The Pathologist 14, 1115. (2015) |
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A perspective on digital and computational pathology |
Ramamurthy B, Coffman FD, Cohen S |
J. Pathol. Inform. 6:29. (2015) |
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MIF inhibits monocytic movement through a non-canonical receptor and disruption of temporal Rho GTPase activities in U-937 cells. |
DiCosmo-Ponticello CJ, Coffman FD, Cohen S, Cohen MC |
Cytokine 69: 47-55. (2014) |
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Chitinase Family Glycoprotein YKL-40 Expression in the Differentiation of Human Mesenchymal Stem Cells Towards Bone, Cartilage, and Neuronal Phenotypes. |
Hoover DJ, Zhu V, Chen R, Briley K, Rameshwar P, Cohen S, Coffman FD |
Differentiation PLoS ONE 8(5): e62491. doi:10.1371/journal.pone.0062491. (2013) |
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Nonerythroid alpha spectrin prevents telomere dysfunction after DNA interstrand cross-link damage. |
Zhang P, Herbig U, Coffman F, Lambert M |
Nuc. Acids Res. 41: 5321-5340. (2013) |
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Impedance measurements in the biomedical sciences. |
Coffman FD, Cohen S |
Modern Trends in Imaging: Pathology at a Crossroads. 185: pp185-206. (2013) |
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Differentiation of Somatic Cells, Stem Cells, and Stem Cell Variants: In Vitro Models. |
Danilenko, M, Coffman, FD, Studzinski, GP |
ENCYCLOPEDIA OF LIFE SCIENCES. John Wiley & Sons, Ltd: Chichester. DOI: 10.1002/9780470015902.a0002565.pub3 (2012) |
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Localization of ORC1 during the cell cycle in human leukemia cells. |
Coffman F.D., Reyes M-L, Brown M, Lambert WC, and Cohen S |
Anal. Cell. Pathol. 34: 355-361. (2011) |
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Biophysical profiling of tumor cell lines. |
Coffman F, Hamid R, Cohen MC, Garippa R, Cohen S. |
Anal. Cell. Pathol. 34:225-234. (2011) |
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